Receive a weekly summary and discussion of the top papers of the week by leading researchers in the field.

In International journal of surgery (London, England)

INTRODUCTION : As AI-assisted diagnosis gained immense popularity, it is imperative to consider its utility and efficiency in the early diagnosis of colorectal cancer, responsible for over 1.8 million cases and 881,000 deaths globally, as reported in 2018. Improved adenoma detection rate, as well as better characterizations of polyps, are significant advantages of AIC. This systematic review investigates the effectiveness of AIC in the early diagnosis of CRC as compared to conventional colonoscopy.

METHODS : Electronic databases such as PubMed/Medline, SCOPUS, and Web of Science (WOS) were reviewed for original studies (randomized controlled trials, observational studies), systematic reviews, and meta-analysis between 2017-2022 utilizing MESH terminology in a broad search strategy. All searches were performed and analyzed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) methodology and were conducted from November,2022. A data extraction form based on the Cochrane Consumers and Communication Review group's extraction template for quality assessment and evidence synthesis was used for data extraction. All included studies considered for bias and ethical criteria and provided valuable evidence to answer the research question.

RESULTS : The database search identified 218 studies, including 87 from PubMed, 60 from SCOPUS, and 71 from Web of Science databases. The retrieved studies from the databases were imported to Rayyan software and a duplicate article check was performed, all duplicate articles were removed after careful evaluation of the data. The abstract and full-text screening was performed in accordance with the following eligibility criteria: STROBE for observational studies; PRISMA for review articles, ENTREQ for narrative studies; and modified JADAD for randomized controlled trials (RCT). This yielded 15 studies that met the requirements for our systematic review and were finally included in the review.

CONCLUSION : AIC is a safe, highly effective screening tool that can increase the detection rate of adenomas, and polyps resulting in early diagnosis of colorectal cancer in adults when compared to conventional colonoscopy. The results of this systematic review prompt further large-scale research to investigate the effectiveness in accordance with gender, race, and socioeconomic status as well as its influence on prognosis and survival rate.

Mehta Aashna, Kumar Harendra, Yazji Katia, Wireko Andrew Awuah, Sivanandan Nagarajan Jai, Ghosh Bikona, Nahas Ahmad, Morales Ojeda Luis, Chandra Ayush, Sharath Medha, Huang Helen, Garg Tulika, Isik Arda

2023-Mar-15