In International journal of biological macromolecules
In the present work, a Gynostemma pentaphyllum herb endophytic fungus of Chaetomium globosum CGMCC 6882 polysaccharide produced from tapioca starch (GCP-TS) with submerged fermentation was analyzed. GCP-TS contains rhamnose, glucosamine, galactose, glucose, mannose, and glucuronic acid in the molar ratio of 6.29: 0.55: 1.12: 22.93: 10.94: 3.54. Its weight-average molecular weight, number-average molecular weight and polydispersity were 4.73 × 104 Da, 4.29 × 104 Da and 1.103, respectively. Antioxidant results showed that GCP-TS had a concentration-dependent scavenging ability against DPPH radical, superoxide anion, hydroxyl radical, and ABTS radical. The corresponding scavenging capacities of GCP-TS aqueous solution at the concentration of 1.0 mg/mL were 45.11 ± 2.52, 43.58 ± 1.97, 36.27 ± 2.48, and 34.39 ± 2.06 %, respectively. Antibacterial activities of GCP-TS against Staphylococcus aureus and Escherichia coli were enhanced with the increase in its concentration, and its bacteriostatic activity against S. aureus was stronger than that against E. coli.
Wang Zichao, Zhou Xueyan, Liang Xiaona, Zheng Xinxin, Shu Zhihan, Sun Qi, Wang Qi, Li Na
2023-Feb-07
Bioactivity, Polysaccharide, Tapioca starch
