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In Fa yi xue za zhi

The succession of microbiota is closely associated with several essential factors, including race, sex, health condition, lifestyle, postmortem interval, etc., and it has great potential application value in forensic medicine. This paper summarizes recent studies on the forensic applications of the microbiome, including individual identification, geographical feature identification, origin identification of the tissue or body fluid, and postmortem interval estimation, and introduces the current machine learning algorithms for microbiology research based on next-generation sequencing data. In addition, the current problems facing forensic microbiomics such as the extraction and preservation of samples, construction of standardization and database, ethical review and practical applicability are discussed. Future multi-omics studies are expected to explore micro ecosystems from a comprehensive and dynamic perspective, to promote the development of forensic microbiomics application.

Lei Fan-Zhang, Chen Man, Mei Shu-Yan, Fang Ya-Ting, Zhu Bo-Feng

2022-Oct-25

analysis of death cause, forensic medicine, geographical feature identification, individual identification, microbiomics, origin identification of tissues and body fluids, postmortem interval estimation, review