In Enfermedades infecciosas y microbiologia clinica (English ed.)
INTRODUCTION : Pleural empyema is an infrequent manifestation of extraintestinal Clostridioidesdifficile infection, with just eight cases reported in literature.
METHODS : We report a new case in a 70-year-old male without comorbidities or evidence of concomitant gastrointestinal disease, and review the previous cases reported in the literature.
RESULTS : The isolate was susceptible to all antimicrobial tested and was negative for A+B toxins. The patient fully recovered after drainages and antimicrobial therapy with amoxicillin-clavulanate and doxycycline.
CONCLUSION : As in the previously reported cases, aspiration was the most plausible hypothesis of mechanism of infection in our patient. Empyema by Clostridioidesdifficile is a diagnostic challenge, since it is necessary to rule out that the isolation of this microorganism in pleural fluid is not a contamination. Furthermore, more evidence is needed for its treatment since data regarding this entity are still scarce.
Alonso-Llada Carmen, Zapico-González Maria Soledad, Caminal-Montero Luis, Fernández Javier
2023-Jan-25
Amoxicilina-clavulánico, Amoxicillin–clavulanate, Aspiration, Broncoaspiración, Clostridioides difficile, Clostridioidesdifficile, Doxiciclina, Doxycycline, Empiema, Empyema
