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In BMC medical imaging

BACKGROUND : The aim was to compare the diffusion tensor imaging (DTI) indices derived from human hearts between 1.5 T and 3.0 T scanners. Additionally, the reproducibility of DTI indices was assessed between 1.5 T and 3.0 T scanners.

METHODS : A total of 18 ex-vivo hearts were derived from patients who underwent heart transplantation. The DTI schemes were performed at 1.5 T and 3.0 T, respectively. Then, the same slices from each ex-vivo heart were selected for image analysis. The student's t-test or Wilcoxon-rank test was used to compare the statistical differences. The agreement of DTI indices was mainly reported as the interclass correlation coefficient (ICC).

RESULTS : No significant differences (all P > 0.05) were found in the DTI indices between 1.5 T and 3.0 T scanners. Interestingly, the ICC of all DTI indices was relatively lower with a low b-value. The reproducibility of the helix angle (HA) was relatively lower when compared to the other DTI indices.

CONCLUSION : The DTI indices of ex-vivo human hearts between 1.5 T and 3.0 T scanners had no significant differences. The consistency of DTI indices needed caution using a low b-value with different field strengths, and the relatively low reproducibility of HA should be considered.

Li Xiaodan, Chen Rui, Xu Xi, Xiao Zebin, Wei Xiaoyu, Yang Yuelong, Zhang Zhongping, Wu Zhigang, Zhu Yanjie, Liu Hui

2023-Jan-25

Cardiovascular magnetic resonance, Comparison, Diffusion tensor imaging, Ex-vivo human heart