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In Mathematical biosciences and engineering : MBE

In this paper, the distributed state estimation problem of genetic regulatory networks (GRNs) with hidden Markovian jumping parameters (HMJPs) is explored. Furthermore, in order to improve the communication efficiency among state estimation sensors, the event-triggered strategy is employed in the distributed framework for sensor networks. Particularly, by considering the fact that the true modes are always unaccessible, a novel nonsynchronous state estimation (NSE) strategy is utilized based on observed hidden mode information. By means of Lyapunov-Krasovski method, sufficient stochastic state estimation analysis and synthesis results are established, such that the concentrations of mRNA and protein in GRNs can be both well estimated by convex optimization. Finally, an illustrative example with relevant simulations results is provided to validate the applicability and effectiveness of the developed state estimation approach.

Ma Chao, Lu Yanfeng

2022-Sep-20

** distributed event-triggered state estimation , genetic regulatory networks , hidden Markovian jumping parameters , nonsynchronous state estimation **