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The Achilles heel of TNBCs: Ferroptosis heterogeneity.

In Cell metabolism ; h5-index 127.0

Resistance to ferroptosis, a form of programmed cell death, is associated with the development of some refractory cancers. In this issue, Yang et al. systematically illustrate the ferroptosis heterogeneity in triple-negative breast cancers (TNBCs) and reveal an innovative immunotherapy combination strategy for the luminal androgen receptor (LAR) subtype of TNBC.

Jiang Li, Gao Xiao-Meng, Cao Ji

2023-Jan-03