In Journal of neuroimaging : official journal of the American Society of Neuroimaging
BACKGROUND AND PURPOSE : Intracranial hemorrhage (ICH) is a common life-threatening condition that must be rapidly diagnosed and treated. However, there is still a lack of consensus regarding treatment, driven to some extent by prognostic uncertainty. While several prediction models for ICH detection have already been published, here we present a deep learning predictive model for ICH prognosis.
METHODS : We included patients with ICH (n = 262), and we trained a custom model for the classification of patients into poor prognosis and good prognosis, using a hybrid input consisting of brain CT images and other clinical variables. We compared it with two other models, one trained with images only (I-model) and the other with tabular data only (D-model).
RESULTS : Our hybrid model achieved an area under the receiver operating characteristic curve (AUC) of .924 (95% confidence interval [CI]: .831-.986), and an accuracy of .861 (95% CI: .760-.960). The I- and D-models achieved an AUC of .763 (95% CI: .622-.902) and .746 (95% CI: .598-.876), respectively.
CONCLUSIONS : The proposed hybrid model was able to accurately classify patients into good and poor prognosis. To the best of our knowledge, this is the first ICH prognosis prediction deep learning model. We concluded that deep learning can be applied for prognosis prediction in ICH that could have a great impact on clinical decision-making. Further, hybrid inputs could be a promising technique for deep learning in medical imaging.
Pérez Del Barrio Amaia, Esteve Domínguez Anna Salut, Menéndez Fernández-Miranda Pablo, Sanz Bellón Pablo, Rodríguez González David, Lloret Iglesias Lara, Marqués Fraguela Enrique, González Mandly Andrés A, Vega José A
2022-Dec-31
deep learning, head CT, hybrid, intracranial hemorrhage, medical image, prediction, prognosis
