In Medical & biological engineering & computing ; h5-index 32.0
Longer-term stability of uncemented femoral stem depends on ossification at bone-implant interface. Although attempts have been made to assess the amount of bone growth using finite element (FE) analysis in combination with a mechanoregulatory algorithm, there has been little research on tissue differentiation patterns on hip stems with proximal macro-textures. The primary goal of this investigation is to qualitatively compare the formation of connective tissues around a femoral implant with/without macro-textures on its proximal surfaces. This study also predicts formation of different tissue phenotypes and their spatio-temporal distribution around a macro-textured femoral stem under routine activities. Results from the study show that non-textured implants (80 to 94%) encourage fibroplasia compared to that in textured implants (71 to 85.38%) under similar routine activity, which might trigger aseptic loosening of implant. Formation of bone was more on medio-lateral sides and towards proximal regions of Gruen zones 2 and 6, which was found to be in line with clinical observations. Fibroplasia was higher under stair climbing (85 to 91%) compared to that under normal walking (71 to 85.38%). This study suggests that stair climbing, although falls under recommended activity, might be detrimental to patient compared to normal walking in the initial rehabilitation period.
Ghosh Rajdeep, Hazra Ankan, Chanda Souptick, Chakraborty Debabrata
2022-Dec-19
Bone growth, Finite element analysis, Mechanoregulation, Tissue differentiation, Uncemented femoral stem
