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In Computational and mathematical methods in medicine

Slime mould algorithm (SMA) is a new metaheuristic algorithm, which simulates the behavior and morphology changes of slime mould during foraging. The slime mould algorithm has good performance; however, the basic version of SMA still has some problems. When faced with some complex problems, it may fall into local optimum and cannot find the optimal solution. Aiming at this problem, an improved SMA is proposed to alleviate the disadvantages of SMA. Based on the original SMA, Gaussian mutation and Levy flight are introduced to improve the global search performance of the SMA. Adding Gaussian mutation to SMA can improve the diversity of the population, and Levy flight can alleviate the local optimum of SMA, so that the algorithm can find the optimal solution as soon as possible. In order to verify the effectiveness of the proposed algorithm, a continuous version of the proposed algorithm, GLSMA, is tested on 33 classical continuous optimization problems. Then, on 14 high-dimensional gene datasets, the effectiveness of the proposed discrete version, namely, BGLSMA, is verified by comparing with other feature selection algorithm. Experimental results reveal that the performance of the continuous version of the algorithm is better than the original algorithm, and the defects of the original algorithm are alleviated. Besides, the discrete version of the algorithm has a higher classification accuracy when fewer features are selected. This proves that the improved algorithm has practical value in high-dimensional gene feature selection.

Qiu Feng, Guo Ran, Chen Huiling, Liang Guoxi