In IEEE transactions on medical imaging ; h5-index 74.0
Magnetic resonance fingerprinting (MRF) is a novel quantitative imaging framework for rapid and simultaneous quantification of multiple tissue properties. 3D MRF allows higher through-plane resolution, but the acquisition process is slow when whole-brain coverage is needed. Existing methods for acceleration mainly rely on GRAPPA for k-space interpolation in the partition-encoding direction, limiting the acceleration factor to 2 or 3. In this work, we replace GRAPPA with a deep learning approach for accurate tissue quantification with greater acceleration. Specifically, a graph convolution network (GCN) is developed to cater to the non-Cartesian spiral sampling trajectories typical in MRF acquisition. The GCN maintains high quantification accuracy with up to 6-fold acceleration and allows 1mm isotropic resolution whole-brain 3D MRF data to be acquired in 3 min and submillimeter 3D MRF (0.8mm) in 5 min, greatly improving the feasibility of MRF in clinical settings.
Cheng Feng, Liu Yilin, Chen Yong, Yap Pew-Thian