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In Biomedical physics & engineering express

Reducing the radiation dose will cause severe image noise and artifacts, and degradation of image quality will also affect the accuracy of diagnosis. To find a solution, we comprise a 2D and 3D concatenating convolutional encoder-decoder (CCE-3D) and the structural sensitive loss (SSL), via transfer learning (TL) for denoising for low-dose computed tomography (LDCT), radiography, and tomosynthesis. The simulation and real-world practicing results show that many of the figures-of-merit (FOMs) increase in both projections (2-3 times) and CT imaging (1.5-2 times). From the PSNR and structural similarity index of measurement (SSIM), the CCE-3D model is effective in denoising but keeps the shape of the structure. Hence, we have developed a denoising model that can be served as a promising tool to be implemented in the next generation X-ray radiography, tomosynthesis, and LDCT systems.

Jin Shih-Chun, Chang Li-Sheng, Wang Yu-Hong, Chen Jyh-Cheng, Tseng Snow H, Liu Tse-Ying


3D concatenating convolutional encoder-decoder (CCE-3D), denoising model, low-dose computed tomography (LDCT), structural sensitive loss (SSL), transfer learning (TL)