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In European journal of nuclear medicine and molecular imaging ; h5-index 66.0

PURPOSE : Total body positron emission tomography (TB-PET) has recently been introduced in nuclear medicine departments. There is a large interest in these systems, but for many centers, the high acquisition cost makes it very difficult to justify their current operational budget. Here, we propose medium-cost long axial FOV scanners as an alternative.

METHODS : Several medium-cost long axial FOV designs are described with their advantages and drawbacks. We describe their potential for higher throughput, more cost-effective scanning, a larger group of indications, and novel research opportunities. The wider spread of TB-PET can also lead to the fast introduction of new tracers (at a low dose), new methodologies, and optimized workflows.

CONCLUSIONS : A medium-cost TB-PET would be positioned between the current standard PET-CT and the full TB-PET systems in investment but recapitulate most advantages of full TB-PET. These systems could be more easily justified financially in a standard academic or large private nuclear medicine department and still have ample research options.

Vandenberghe Stefaan, Karakatsanis Nicolas A, Akl Maya Abi, Maebe Jens, Surti Suleman, Dierckx Rudi A, Pryma Daniel A, Nehmeh Sadek A, Bouhali Othmane, Karp Joel S

2022-Sep-30

Deep learning, Dose reduction, Positron emission tomography, Total-body PET