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In Computers in biology and medicine

BACKGROUND : The coronavirus disease (COVID-19) effected a global health crisis in 2019, 2020, and beyond. Currently, methods such as temperature detection, clinical manifestations, and nucleic acid testing are used to comprehensively determine whether patients are infected with the severe acute respiratory syndrome coronavirus 2. However, during the peak period of COVID-19 outbreaks and in underdeveloped regions, medical staff and high-tech detection equipment were limited, resulting in the continued spread of the disease. Thus, a more portable, cost-effective, and automated auxiliary screening method is necessary.

OBJECTIVE : We aim to apply a machine learning algorithm and non-contact monitoring system to automatically screen potential COVID-19 patients.

METHODS : We used impulse-radio ultra-wideband radar to detect respiration, heart rate, body movement, sleep quality, and various other physiological indicators. We collected 140 radar monitoring data from 23 COVID-19 patients in Wuhan Tongji Hospital and compared them with 144 radar monitoring data from healthy controls. Then, the XGBoost and logistic regression (XGBoost + LR) algorithms were used to classify the data according to patients and healthy subjects.

RESULTS : The XGBoost + LR algorithm demonstrated excellent discrimination (precision = 92.5%, recall rate = 96.8%, AUC = 98.0%), outperforming other single machine learning algorithms. Furthermore, the SHAP value indicates that the number of apneas during REM, mean heart rate, and some sleep parameters are important features for classification.

CONCLUSION : The XGBoost + LR-based screening system can accurately predict COVID-19 patients and can be applied in hotels, nursing homes, wards, and other crowded locations to effectively help medical staff.

Dong Chunjiao, Qiao Yixian, Shang Chunheng, Liao Xiwen, Yuan Xiaoning, Cheng Qin, Li Yuxuan, Zhang Jianan, Wang Yunfeng, Chen Yahong, Ge Qinggang, Bao Yurong

2021-Nov-03

COVID-19, Logistic regression, Non-contact vital signs, Screening system, XGBoost