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In Journal of medical Internet research ; h5-index 88.0

The novel coronavirus (SARS-CoV-2) and its related disease, COVID-19, are exponentially increasing across the world, yet there is still uncertainty about the clinical phenotype. Natural Language Processing (NLP) and machine learning may hold one key to quickly identify individuals at high risk for COVID-19 and understand key symptoms in its clinical manifestation and presentation. Data on such symptoms may not be accurately synthesized into patient records due to the pressing need to treat patients in overburdened health care settings. In this scenario, clinicians may focus on documenting widely reported symptoms that appear to confirm the diagnosis of COVID-19, at the expense of infrequently reported symptoms. While NLP solutions can play a key role in creating clinical phenotypes of COVID-19, they are limited by the resulting limitations in EHR data. A comprehensive record of the clinic visit is required-an audio recording may be the answer. A recording of the clinic visit represents a more comprehensive record of patient-reported symptoms. If done at scale, a combination of data from the EHR and recordings of clinic visits can be used to power NLP and machine learning models, quickly creating a clinical phenotype of COVID-19. We propose the creation of a pipeline from the audio/video recording of clinic visits to the clinical symptomatology model and prediction of COVID-19 infection. With vast amounts of data available, we believe a prediction model can be quickly developed that could promote the accurate screening of individuals at risk of COVID-19 and identify patient characteristics predicting a greater risk of a more severe infection. If clinical encounters are recorded and our NLP is adequately refined, then benchtop-virology will be better informed. While recordings of clinic visits are not the panacea to this pandemic, they are a low cost option with many potential benefits that have only just begun to be explored.

Barr Paul J, Ryan James, Jacobson Nicholas C

2021-Jan-18