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In Journal of clinical medicine

BACKGROUND AND AIMS : Endoscopic ultrasonography (EUS) is a useful diagnostic modality for evaluating gastric mesenchymal tumors; however, differentiating gastrointestinal stromal tumors (GISTs) from benign mesenchymal tumors such as leiomyomas and schwannomas remains challenging. For this reason, we developed a convolutional neural network computer-aided diagnosis (CNN-CAD) system that can analyze gastric mesenchymal tumors on EUS images.

METHODS : A total of 905 EUS images of gastric mesenchymal tumors (pathologically confirmed GIST, leiomyoma, and schwannoma) were used as a training dataset. Validation was performed using 212 EUS images of gastric mesenchymal tumors. This test dataset was interpreted by three experienced and three junior endoscopists.

RESULTS : The sensitivity, specificity, and accuracy of the CNN-CAD system for differentiating GISTs from non-GIST tumors were 83.0%, 75.5%, and 79.2%, respectively. Its diagnostic specificity and accuracy were significantly higher than those of two experienced and one junior endoscopists. In the further sequential analysis to differentiate leiomyoma from schwannoma in non-GIST tumors, the final diagnostic accuracy of the CNN-CAD system was 72.5%, which was significantly higher than that of two experienced and one junior endoscopists.

CONCLUSIONS : Our CNN-CAD system showed high accuracy in diagnosing gastric mesenchymal tumors on EUS images. It may complement the current clinical practices in the EUS diagnosis of gastric mesenchymal tumors.

Kim Yoon Ho, Kim Gwang Ha, Kim Kwang Baek, Lee Moon Won, Lee Bong Eun, Baek Dong Hoon, Kim Do Hoon, Park Jun Chul

2020-Sep-29

artificial intelligence, endoscopic ultrasonography, gastrointestinal stromal tumor, mesenchymal tumor, stomach