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In Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

BACKGROUND AND AIMS : Improving the rate of polyp detection is an important measure to prevent colorectal cancer (CRC). Real-time automatic polyp detection systems, through deep learning methods, can learn and perform specific endoscopic tasks previously performed by endoscopists. The purpose of this study was to explore whether a high-performance, real-time automatic polyp detection system could improve the polyp detection rate (PDR) in the actual clinical environment.

METHODS : The selected patients underwent same-day, back-to-back colonoscopies in a random order, with either traditional colonoscopy or artificial intelligence (AI)-assisted colonoscopy performed first by different experienced endoscopists (> 3000 colonoscopies). The primary outcome was the PDR. It was registered with . (NCT047126265).

RESULTS : In this study, we randomized 150 patients. The AI system significantly increased the PDR (34.0% vs 38.7%, p < 0.001). In addition, AI-assisted colonoscopy increased the detection of polyps smaller than 6 mm (69 vs 91, p < 0.001), but no difference was found with regard to larger lesions.

CONCLUSIONS : A real-time automatic polyp detection system can increase the PDR, primarily for diminutive polyps. However, a larger sample size is still needed in the follow-up study to further verify this conclusion.

TRIAL REGISTRATION : Identifier: NCT047126265.

Luo Yuchen, Zhang Yi, Liu Ming, Lai Yihong, Liu Panpan, Wang Zhen, Xing Tongyin, Huang Ying, Li Yue, Li Aiming, Wang Yadong, Luo Xiaobei, Liu Side, Han Zelong


Artificial intelligence, Colonoscopy, Computer-aided diagnose