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In European journal of medicinal chemistry ; h5-index 72.0

Neuroblastoma (NB) is one of the most common pediatric malignancies. Easy metastasis, poor prognosis, and a high degree of heterogeneity of NB hinder its successful treatment. Several different therapeutic strategies have been developed to overcome these problems, including differentiation and targeted therapy. In this review, we summarize the recent development of differentiation modulators and targeted agents for treating NB. Several promising targets of NB were also discussed.

Jin Zegao, Lu Yang, Wu Yizhe, Che Jinxin, Dong Xiaowu

2020-Sep-08

Differentiation therapy, Neuroblastoma, Targeted therapy