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In Alzheimer's & dementia (New York, N. Y.)

Introduction : Ability to determine dementia prevalence in low- and middle-income countries (LMIC) remains challenging because of frequent lack of data and large discrepancies in dementia case ascertainment.

Methods : High likelihood of dementia was determined with hierarchical clustering after principal component analysis applied in 10 population surveys of aging: HRS (USA, 2014), SHARE (Europe and Israel, 2015), MHAS (Mexico, 2015), ELSI (Brazil, 2016), CHARLS (China, 2015), IFLS (Indonesia, 2014-2015), LASI (India, 2016), SAGE-Ghana (2007), SAGE-South Africa (2007), SAGE-Russia (2007-2010). We approximated dementia prevalence using weighting methods.

Results : Estimated numbers of dementia cases were: China, 40.2 million; India, 18.0 million; Russia, 5.2 million; Europe and Israel, 5.0 million; United States, 4.4 million; Brazil, 2.2 million; Mexico, 1.6 million; Indonesia, 1.3 million; South Africa, 1.0 million; Ghana, 319,000.

Discussion : Our estimations were similar to prior ones in high-income countries but much higher in LMIC. Extrapolating these results globally, we suggest that almost 130 million people worldwide were living with dementia in 2015.

Cleret de Langavant Laurent, Bayen Eléonore, Bachoud-Lévi Anne-Catherine, Yaffe Kristine


dementia, low‐ and middle‐income countries, machine learning, population survey, prevalence