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In Korean journal of radiology

The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. The nucleic acid test or genetic sequencing serves as the gold standard method for confirmation of infection, yet several recent studies have reported false-negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). Here, we report two representative false-negative cases and discuss the supplementary role of clinical data with rRT-PCR, including laboratory examination results and computed tomography features. Coinfection with SARS-COV-2 and other viruses has been discussed as well.

Li Dasheng, Wang Dawei, Dong Jianping, Wang Nana, Huang He, Xu Haiwang, Xia Chen


COVID-19, Computed tomography, False-negative results, Laboratory examination, SARS-COV-2, rRT-PCR