Receive a weekly summary and discussion of the top papers of the week by leading researchers in the field.

In Genome biology ; h5-index 114.0

We describe ReorientExpress, a method to perform reference-free orientation of transcriptomic long sequencing reads. ReorientExpress uses deep learning to correctly predict the orientation of the majority of reads, and in particular when trained on a closely related species or in combination with read clustering. ReorientExpress enables long-read transcriptomics in non-model organisms and samples without a genome reference without using additional technologies and is available at

Ruiz-Reche Angel, Srivastava Akanksha, Indi Joel A, de la Rubia Ivan, Eyras Eduardo