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In PloS one ; h5-index 176.0

As a powerful imaging tool, X-ray computed tomography (CT) allows us to investigate the inner structures of specimens in a quantitative and nondestructive way. Limited by the implementation conditions, CT with incomplete projections happens quite often. Conventional reconstruction algorithms are not easy to deal with incomplete data. They are usually involved with complicated parameter selection operations, also sensitive to noise and time-consuming. In this paper, we reported a deep learning reconstruction framework for incomplete data CT. It is the tight coupling of the deep learning U-net and CT reconstruction algorithm in the domain of the projection sinograms. The U-net estimated results are not the artifacts caused by the incomplete data, but the complete projection sinograms. After training, this framework is determined and can reconstruct the final high quality CT image from a given incomplete projection sinogram. Taking the sparse-view and limited-angle CT as examples, this framework has been validated and demonstrated with synthetic and experimental data sets. Embedded with CT reconstruction, this framework naturally encapsulates the physical imaging model of CT systems and is easy to be extended to deal with other challenges. This work is helpful to push the application of the state-of-the-art deep learning techniques in the field of CT.

Dong Jianbing, Fu Jian, He Zhao